Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep966 | Pituitary - Clinical | ECE2017

Gender differences in real-life GH dosing patterns in adults with GH deficiency (AGHD): experience from a Registry in France

Borson-Chazot Francoise , Hacques Evguenia , Pascal-Vigneron Veronique , Salenave Sylvie , Villette Beatrice

Introduction: Usually GHD women require higher GH doses than males, especially those with exogenous oestrogens (guidelines). This fact was assessed in real-life practice in France.Methods: Data were from a Registry in 84 sites treating AGHD (Norditropin®) up to 5 years. Naïve patients did not receive GH 6 months before inclusion. Statistics were descriptive.Results: 328 patients (129 naïve) were included; mean age 49...

ea0056p741 | Growth hormone IGF axis - basic | ECE2018

IGF1 level and GH dose adjustmentin adults with GH deficiency (AGHD): experience from a Registry in France

Borson-Chazot Francoise , Pascal-Vigneron Veronique , Salenave Sylvie , Hacques Evguenia , Villette Beatrice

Objective: IGF1 is the most useful serum marker for GH dose titration in adults. The authors focused on the GH dose adjustment with extreme IGF1 values (<−2S.D.; >+2S.D.).Methods: French observational study of AGHD patients treated with Norditropin®.Prospective follow up until 5 years.Results (median [Q1; Q3]):: 328 AGHD, 39.2±14.3 years old wer...